Tuesday, May 16, 2023

Fentanyl Exposure

 From PsyPost:

New research sheds light on the brain circuits involved in addiction to opioids like fentanyl. The findings, published in Cell Reports, indicate that that chronic opioid exposure triggers a series of changes in the brain that results in a hypodopaminergic state. This state may underlie the mechanism of anxiety-like behaviors during acute opioid withdrawal.

Opioid addiction has become a global epidemic, with millions of people suffering from its devastating effects. Opioids are highly addictive drugs that act on the brain’s reward system, producing feelings of pleasure and euphoria. However, with prolonged use, opioids can lead to a range of negative emotional states, including anxiety, depression, and irritability, which can trigger relapse. (Read more.)


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